Variants of ribonuclease inhibitor that resist oxidation
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چکیده
منابع مشابه
Variants of ribonuclease inhibitor that resist oxidation BYUNG - MOON KIM , L .
Human ribonuclease inhibitor ~hRI! is a cytosolic protein that protects cells from the adventitious invasion of pancreatictype ribonucleases. hRI has 32 cysteine residues. The oxidation of these cysteine residues to form disulfide bonds is a rapid, cooperative process that inactivates hRI. The most proximal cysteine residues in native hRI are two pairs that are adjacent in sequence: Cys94 and C...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2008
ISSN: 0961-8368
DOI: 10.1110/ps.8.2.430